Xfer Records Serum VSTi for MacOS X is an imposing tabular wave synthesizer with top quality sound. It has been equipped with a visually pleasing and intuitive user interface. It has been equipped with a built-in wave table editor which will make music production simple and easy. You can also download U-He ACE VST for Mac OS X.
Serum Vst Mac Download
Xfer Records Serum VSTi for MacOS X has got loads of different wave tables plus it has got a unison generator that provides up to 16 votes and lets you adjust the volume to child ration between them flexibly. The sound that is produced is crisp, lively and modern. Xfer Records Serum VSTi for MacOS X allows you to import as well as create your own wavetables. It has got imposing oscillators which will ensure that the sound in Serum will be crisp, transparent and clean. You can enhance your audio content with loads of filters which are available. It has been equipped with more than 450 presets as well as 144 wave tables. All in all Xfer Records Serum VSTi for MacOS X is an imposing tabular wave synthesizer with top quality sound. You can also download ArtsAcoustic Reverb VST for Mac OS X.
I did ofc. I also installed it and It works i just wanted to know this beforehand. For people who havent had any version of serum before these folders just dont exist and the instructions are kind of misleading.
Serum is an Advanced Wavetable Synthesizer designed and created by Xfer. It is a VST instrument plugin compatible with all major DAWs. Serum comes with an endless list of features including, but not limited to, an instantly recongizable and slick interface, 10 unique effects, powerful wave shaping tools and dual wavetable oscillators. It also comes with over 450 state of the art presets 144 wavetables and can be used on both Windows and Mac devices. If you are a preset user, than Serum is a must-buy.What are serum presets?Presets is just an abbreviation for preset settings. When you open any VST synth inside your DAW for the first time and play a random note, you will encounter two kinds of default settings. The initial preset will be either a generic waveform (e.g., saw wave) or a more sophisticated preset sound that is supposed to demonstrate the power and versatility of the synth.
Locate first the default serum preset folder location (Mac: \Library\Audio\Presets\Xfer Records\Serum Presets, PC: \Documents\Xfer\Serum Presets, or Menu > show serum presets folder) then check if the folder exists and contains files and subfolders.
Locate first the default serum preset folder location (Mac: \\Library\\Audio\\Presets\\Xfer Records\\Serum Presets, PC: \\Documents\\Xfer\\Serum Presets, or Menu > show serum presets folder) then check if the folder exists and contains files and subfolders.
Lung disease (LD) due to non-tuberculous mycobacteria is an important clinical concern. Mycobacterium avium complex (MAC) is one of the most common causative agents but the diagnosis of MAC-LD remains challenging. Detection of serum IgA antibody against MAC glycopeptidolipid (GPL) has recently been shown to improve the diagnosis of MAC-LD, but has yet to be validated worldwide.
There were 56 patients with MAC-LD, 11 with MAC contamination, 13 M. kansasii-LD, 26 LD due to rapidly-growing mycobacteria (RGM), 48 pulmonary tuberculosis, and 42 household contacts of patients with TB. Patients with MAC-LD were older and 32% of them had an underlying co-morbidity. By logistic regression, serum MAC-GPL IgA level was an independent predictor of MAC-LD among the study subjects and those with culture-positive specimens for MAC. By the receiver operating characteristic curve, serum MAC-GPL IgA had a good power to discriminate MAC-LD from MAC contamination. Under the optimal cut-off value of 0.73 U/mL, its sensitivity and specificity were 60% and 91%, respectively. Among MAC-LD patients, presence of co-morbidity was associated with MAC-GPL
Among sero-diagnostic methods, detection of serum immunoglobulin A (IgA) antibody against MAC glycopeptidolipid (GPL), an important antigenic component of MAC bacterial wall, has been recently developed. It shows good diagnostic performance in Japan (MAC-GPL IgA, Tauns Laboratory Inc., Shizuoka, Japan) [9,10]. However, a study conducted in the United States reveals that the test is specific but less sensitive (70%) when the same cut-off value (0.7 U/mL) is used, despite sufficient sensitivity (80%) obtained at 0.3 U/mL as the cut-off value [11]. The studies in Japan have included immunocompetent patients, but a small number of immunocompromised patients such as lung cancer, and did not examined patients with diseases due to rapidly growing mycobacteria (RGM) possessing glycopeptidolipid antigen such as M. abscessus, M. fortuitum, and M. chelonae [9,10]. Therefore, the sero-diagnostic test requires validation in different ethnicities and geographic locations with variable background prevalence of M. tuberculosis and NTM. This study examined the clinical availability of the sero-diagnostic test for MAC-GPL IgA, including sensitivity and specificity, in Taiwan.
Regarding MAC-GPL IgA, MAC-LD patients had significantly higher serum levels than all of the other groups (Figure 1). Multivariate logistic regression revealed that age (odds ratio [OR]: 1.032; 95% CI: 1.005-1.060), presence of autoimmune disease (OR: 4.884; 95% CI: 1.038-22.971), and serum MAC-GPL IgA antibody level (OR: 1.325; 95% CI: 1.144-1.536) were independent predictors of MAC-LD (Table 2). As regards patients with respiratory specimen(s) culture-positive for MAC, only MAC-GPL IgA level (OR: 2.856; 95% CI: 1.045-7.805) remained a significant factor for differentiating MAC-LD from MAC contamination.
The median MAC-GPL IgA serum level was similar between those with and without prior TB history (1.32 vs. 1.47 U/ml, p = 0.982 by Mann-Whitney U test). The number of positive culture, disease duration before blood sampling, started NTM treatment, and radiographic pattern were not significantly correlated with MAC-GPL IgA level. Among the 56 MAC-LD patients, the average MAC-GPL IgA was similar in the 10 with bronchoscopic specimen(s) positive for MAC and the other 46 without (4.11 vs. 4.99 U/mL, p=0.694).
In the present study, serum MAC-GPL IgA level is higher in MAC-LD than MAC contamination and other mycobacterial lung diseases. Using a cut-off value of 0.73 U/ml leads to an intermediate sensitivity but excellent specificity for identifying patients with MAC-LD. In MAC-LD, immuno-competence is independently associated with higher serum MAC-GPL IgA level.
Inflammatory markers like C-reactive protein, procalcitonin, and interferon-gamma are poorly associated with NTM-LD. Soluble triggering receptors expressed on myeloid cell-1 have better correlation with NTM-LD though these are not pathognomonic [7]. In contrast, MAC-GPL antibody is more specific to MAC-LD and has been developed since the last decade [9,10]. Such GPL belong to a class of glycolipids produced by several NTM [15,16] and is an important element in NTM cell wall. GPL is located in the outmost layer, and is thus very antigenic [16]. A previous study conducted in a Japanese population reported 100% specificity and 84% sensitivity in differentiating MAC-LD from other lung disease using a cut-off value of 0.7 U/ml for MAC-GPL IgA serum level [10]. Such finding suggests that GPL of MAC is antigenic and its antibody maybe a good diagnostic marker.
In conclusion, serum level of MAC-GPL IgA antibody is higher in MAC-LD than MAC contamination and other lung diseases. Using a cut-off value of 0.73 U/mL leads to an intermediate sensitivity (60%) but good specificity (91%) for differentiating MAC-LD from MAC contamination. This might be helpful in suggesting pulmonary infection by MAC when a respiratory specimen was culture-positive for MAC but further invasive diagnostic procedure like bronchoscopy is risky. Careful consideration is needed while using MAC-GPL IgA antibody in immuno-compromised hosts.
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Introduction: Inflammation is the forerunner to fibrosis and premature aging in various systemic diseases. Hence, we hypothesized that idiopathic inflammatory myopathies (IIM) may exhibit accelerated senescence, and the serum myostatin (MSTN):follistatin system may be a reflection of early senescence events in the muscle. Methods: Patients with IIM (ACR/EULAR criteria) were recruited (2017-2019) for comparison with healthy and disease controls (DCs). Those with active infection, pregnancy, renal dysfunction, or chronic kidney disease were excluded from the study. MSTN and follistatin were estimated in sera using ELISA (R&D systems, USA). Juvenile myositis and young adults (18-40 years) were subsequently analyzed separately. Nonparametric tests were used for paired and unpaired analysis. Results expressed as median and interquartile range. Results: A total of 84 myositis (3 juvenile myositis, 40 DM, 30 PM, 11 overlap) patients (68 females) with median age 38 (27-47.0) years and median disease duration of 0.9 (2.3-5.1) years were included. Serum MSTN was lower in IIM than in healthy control (149.3 vs. 243.6 P
93 schizophrenic patients with severely poor adjusted BUA values and 93 age and gender matched patients with normal adjusted BUA values from a previous survey study were selected. Data were collected via questionnaires and via reviews of antipsychotic medications. Blood samples were drawn, and serum levels of prolactin, estradiol, testosterone, magnesium, calcium, phosphate, osteocalcin, Cross-linked N-teleopeptide of type I collagen (NTX), thyroid hormone and parathyroid hormone were checked. The association between BUA levels and serum levels of the above items, along with the type of received antipsychotic medication, was evaluated. 2ff7e9595c
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